Interleukin 4 in Systemic Sclerosis: Not Just an Increase

Effect of Vitamin D treatment on Interleukin-2 and Interleukin-4 Genes expression in Multiple Sclerosis

Introduction: Multiple sclerosis is a chronic inflammatory disease of central nervous system. The etiology of MS is slightly known, but genetic and environmental factors are reported. Vitamin D regulates gene expression and affects target cell functions. The aim of this study was to investigate the expression variation of IL-2 and IL-4 genes under vitamin D supplementation in patients with mult...

Systemic lupus erythematosus: not just a rash.

A previously healthy 11-year-old Chinese girl presented to the accident and emergency department with a 4-month history of persistent rashes over her palms and soles, and a 1-week history of malaise and low-grade fever. Her general practitioner had suggested that the rash could have been caused by hand, foot and mouth disease. On examination, she had non-blanching erythematous macular lesions w...

Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?

Title Clinical association of serum interleukin 17 levels in systemic sclerosis: Is systemic sclerosis a Th17 disease? Author(s) Murata, Maki; Fujimoto, Manabu; Komura, Kazuhiro; Matsushita, Takashi; Hamaguchi, Yasuhito; Hasegawa, Minoru; Sato, Shinichi; Takehara, Kazuhiko Citation Journal of Dermatological Science, 50(3), pp.240-242; 2008 Issue Date 2008-03-07 URL http://hdl.handle.net/10069/1...

Jets are not just 4 - momenta !

Relationship between interleukin-6 and cardiac involvement in systemic sclerosis.

OBJECTIVES To explore the relationship between IL-6 levels and echocardiographic abnormalities, and N-terminal probrain natriuretic peptide (NT-proBNP) levels in SSc patients and to correlate tested parameters with European Scleroderma Activity (EUSTAR) score. METHODS This case-control study included 31 SSc patients with preserved left ventricular ejection fraction (LVEF) and 32 matched healt...